Isolation and structural identification of 9hydroxy-9desmethyl-cyclosporine.

Isolation and Identification of a Sulfide/Sulfoxide Monooxygenase Gene from a Newly Isolated Rhodococcus Sp. Strain FMF

Rhodococcus FMF is a gram-positive bacterium isolated for the first time from soil samples of Tabriz refinery in Iran. This microorganism is able to catabolize dibenzothiophene to 2-hydroxybiphenyl and inorganic sulfur without the destruction of carbon-carbon bonds. Three structural genes, dszA, dszB, and dszC have been characterized and shown to be responsible for this phenotype. In this work,...

A Review on Isolation and Identification of Endophytic Actinobacteria, Their Chemical Structure, Bioactive Compounds, and Potential Medical-Pharmaceutical Applications

 Over recent years, nosocomial infections, and the morbidity and mortality associated with pathogenic bacteria have dramatically increased due to antibiotic resistance and imposed significant burdens on the global health system. Critical shortage of effective therapeutics against multidrug-resistant bacteria highlights the need for development of novel antibiotics. Actinobacteria are well-known...

Isolation and Identification of Avian Influenza Virus H9N2 Subtype

HPLC-SPE-NMR: a productivity tool in natural products research

Natural products provide excellent potential leads for drug development because of their chemical diversity and biological functionality. However, the productivity of discovery of new, pharmacologically active natural products has traditionally been low due to inherent difficulties and costs associated with extract dereplication, i.e., isolation, purification and structure elucidation of indivi...

HPLC-SPE-NMR: a productivity tool in natural products research

Natural products provide excellent potential leads for drug development because of their chemical diversity and biological functionality. However, the productivity of discovery of new, pharmacologically active natural products has traditionally been low due to inherent difficulties and costs associated with extract dereplication, i.e., isolation, purification and structure elucidation of indivi...